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Analysis of nanobody paratopes reveals greater diversity than classical antibodies

Nanobodies (Nbs) are a class of antigen-binding protein derived from camelid immune systems, which achieve equivalent binding affinities and specificities to classical antibodies (Abs) despite being comprised of only a single variable domain. Here, we use a data set of 156 unique Nb:antigen complex...

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Detalles Bibliográficos
Autores principales: Mitchell, Laura S, Colwell, Lucy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277174/
https://www.ncbi.nlm.nih.gov/pubmed/30053276
http://dx.doi.org/10.1093/protein/gzy017

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