Cargando…
Analysis of nanobody paratopes reveals greater diversity than classical antibodies
Nanobodies (Nbs) are a class of antigen-binding protein derived from camelid immune systems, which achieve equivalent binding affinities and specificities to classical antibodies (Abs) despite being comprised of only a single variable domain. Here, we use a data set of 156 unique Nb:antigen complex...
Autores principales: | Mitchell, Laura S, Colwell, Lucy J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277174/ https://www.ncbi.nlm.nih.gov/pubmed/30053276 http://dx.doi.org/10.1093/protein/gzy017 |
Ejemplares similares
-
Paratope diversity of anti-prothrombin antibodies
por: Cucnik, S, et al.
Publicado: (2003) -
Nanobody Paratope Ensembles in Solution Characterized by MD Simulations and NMR
por: Fernández-Quintero, Monica L., et al.
Publicado: (2022) -
Mapping paratopes of nanobodies using native mass spectrometry and ultraviolet photodissociation
por: Macias, Luis A., et al.
Publicado: (2022) -
Comparative analysis of nanobody sequence and structure data
por: Mitchell, Laura S., et al.
Publicado: (2018) -
Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins
por: Sherwood, Laura Jo, et al.
Publicado: (2019)