CLN8 is an ER cargo receptor that regulates lysosome biogenesis

Organelle biogenesis requires proper transport of proteins from their site of synthesis to their target subcellular compartment(1–3). Lysosomal enzymes are synthesized in the endoplasmic reticulum (ER) and traffic through the Golgi complex before being transferred to the endolysosomal system(4–6), b...

Descripción completa

Detalles Bibliográficos
Autores principales: di Ronza, Alberto, Bajaj, Lakshya, Sharma, Jaiprakash, Sanagasetti, Deepthi, Lotfi, Parisa, Adamski, Carolyn Joy, Collette, John, Palmieri, Michela, Amawi, Abdallah, Popp, Lauren, Chang, Kevin Tommy, Meschini, Maria Chiara, Leung, Hon-Chiu Eastwood, Segatori, Laura, Simonati, Alessandro, Sifers, Richard Norman, Santorelli, Filippo Maria, Sardiello, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277210/
https://www.ncbi.nlm.nih.gov/pubmed/30397314
http://dx.doi.org/10.1038/s41556-018-0228-7

Ejemplares similares

Ejemplares similares