PTEN Hamartoma Tumor Syndrome and Immune Dysregulation()()()

Carriers of a pathogenic germline mutations in the PTEN gene, a well-known tumor suppressor gene, are at increased risk of multiple benign and malignant tumors, e.g. breast, thyroid, endometrial and colon cancer. This is called PTEN Hamartomous Tumor Syndrome (PHTS). PHTS patients may also have an i...

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Detalles Bibliográficos
Autores principales: Eissing, Marc, Ripken, Lise, Schreibelt, Gerty, Westdorp, Harm, Ligtenberg, Marjolijn, Netea-Maier, Romana, Netea, Mihai G., de Vries, I. Jolanda M., Hoogerbrugge, Nicoline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Review article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277246/
https://www.ncbi.nlm.nih.gov/pubmed/30504085
http://dx.doi.org/10.1016/j.tranon.2018.11.003

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