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Angiotensin Type 1 Receptor Antagonists Protect Against Alpha-Synuclein-Induced Neuroinflammation and Dopaminergic Neuron Death

The loss of dopaminergic neurons and α-synuclein accumulation are major hallmarks of Parkinson’s disease (PD), and it has been suggested that a major mechanism of α-synuclein toxicity is microglial activation. The lack of animal models that properly reproduce PD, and particularly the underlying synu...

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Detalles Bibliográficos
Autores principales: Rodriguez-Perez, Ana I., Sucunza, Diego, Pedrosa, Maria A., Garrido-Gil, Pablo, Kulisevsky, Jaime, Lanciego, Jose L., Labandeira-Garcia, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277291/
https://www.ncbi.nlm.nih.gov/pubmed/29987762
http://dx.doi.org/10.1007/s13311-018-0646-z

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