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MacroH2A1 chromatin specification requires its docking domain and acetylation of H2B lysine 20

The histone variant macroH2A1 localizes to two functionally distinct chromatin subtypes marked by either H3K27me3 or H2B acetylations, where it is thought to directly regulate transcription. The recent finding, that macroH2A1 regulates mitochondrial respiration by globally dampening PARP activity, r...

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Detalles Bibliográficos
Autores principales:	Ruiz, Penelope D., Gamble, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277393/ https://www.ncbi.nlm.nih.gov/pubmed/30510186 http://dx.doi.org/10.1038/s41467-018-07189-8

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