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SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain

SIRT3, the primary mitochondrial deacetylase, plays a significant role in enhancing the function of mitochondrial proteins. Downregulation of SIRT3 is a key component of metabolic syndrome, a precondition for obesity, diabetes and cardiovascular diseases. In this study, we examined the effects of br...

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Detalles Bibliográficos
Autores principales:	Tyagi, Alpna, Nguyen, Christy U, Chong, Thomas, Michel, Cole R, Fritz, Kristofer S., Reisdorph, Nichole, Knaub, Leslie, Reusch, Jane E. B., Pugazhenthi, Subbiah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277395/ https://www.ncbi.nlm.nih.gov/pubmed/30510203 http://dx.doi.org/10.1038/s41598-018-35890-7

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