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Molecular diagnostics in medical mycology

Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal identification compared to that of bacteria and viruses.These problems are exacerbated by the fact that pa...

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Autores principales: Wickes, Brian L., Wiederhold, Nathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277409/
https://www.ncbi.nlm.nih.gov/pubmed/30510235
http://dx.doi.org/10.1038/s41467-018-07556-5
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author Wickes, Brian L.
Wiederhold, Nathan P.
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Wiederhold, Nathan P.
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description Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal identification compared to that of bacteria and viruses.These problems are exacerbated by the fact that patients with fungal infections are often immunosuppressed, which predisposes to infections from both commonly and rarely seen fungi. In this review, we discuss current and future molecular technologies used for fungal identification, and some of the problems associated with development and implementation of these technologies in today’s clinical microbiology laboratories.
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spelling pubmed-62774092018-12-05 Molecular diagnostics in medical mycology Wickes, Brian L. Wiederhold, Nathan P. Nat Commun Review Article Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal identification compared to that of bacteria and viruses.These problems are exacerbated by the fact that patients with fungal infections are often immunosuppressed, which predisposes to infections from both commonly and rarely seen fungi. In this review, we discuss current and future molecular technologies used for fungal identification, and some of the problems associated with development and implementation of these technologies in today’s clinical microbiology laboratories. Nature Publishing Group UK 2018-12-03 /pmc/articles/PMC6277409/ /pubmed/30510235 http://dx.doi.org/10.1038/s41467-018-07556-5 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review Article
Wickes, Brian L.
Wiederhold, Nathan P.
Molecular diagnostics in medical mycology
title Molecular diagnostics in medical mycology
title_full Molecular diagnostics in medical mycology
title_fullStr Molecular diagnostics in medical mycology
title_full_unstemmed Molecular diagnostics in medical mycology
title_short Molecular diagnostics in medical mycology
title_sort molecular diagnostics in medical mycology
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277409/
https://www.ncbi.nlm.nih.gov/pubmed/30510235
http://dx.doi.org/10.1038/s41467-018-07556-5
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