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Molecular diagnostics in medical mycology
Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal identification compared to that of bacteria and viruses.These problems are exacerbated by the fact that pa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277409/ https://www.ncbi.nlm.nih.gov/pubmed/30510235 http://dx.doi.org/10.1038/s41467-018-07556-5 |
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author | Wickes, Brian L. Wiederhold, Nathan P. |
author_facet | Wickes, Brian L. Wiederhold, Nathan P. |
author_sort | Wickes, Brian L. |
collection | PubMed |
description | Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal identification compared to that of bacteria and viruses.These problems are exacerbated by the fact that patients with fungal infections are often immunosuppressed, which predisposes to infections from both commonly and rarely seen fungi. In this review, we discuss current and future molecular technologies used for fungal identification, and some of the problems associated with development and implementation of these technologies in today’s clinical microbiology laboratories. |
format | Online Article Text |
id | pubmed-6277409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-62774092018-12-05 Molecular diagnostics in medical mycology Wickes, Brian L. Wiederhold, Nathan P. Nat Commun Review Article Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal identification compared to that of bacteria and viruses.These problems are exacerbated by the fact that patients with fungal infections are often immunosuppressed, which predisposes to infections from both commonly and rarely seen fungi. In this review, we discuss current and future molecular technologies used for fungal identification, and some of the problems associated with development and implementation of these technologies in today’s clinical microbiology laboratories. Nature Publishing Group UK 2018-12-03 /pmc/articles/PMC6277409/ /pubmed/30510235 http://dx.doi.org/10.1038/s41467-018-07556-5 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Review Article Wickes, Brian L. Wiederhold, Nathan P. Molecular diagnostics in medical mycology |
title | Molecular diagnostics in medical mycology |
title_full | Molecular diagnostics in medical mycology |
title_fullStr | Molecular diagnostics in medical mycology |
title_full_unstemmed | Molecular diagnostics in medical mycology |
title_short | Molecular diagnostics in medical mycology |
title_sort | molecular diagnostics in medical mycology |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277409/ https://www.ncbi.nlm.nih.gov/pubmed/30510235 http://dx.doi.org/10.1038/s41467-018-07556-5 |
work_keys_str_mv | AT wickesbrianl moleculardiagnosticsinmedicalmycology AT wiederholdnathanp moleculardiagnosticsinmedicalmycology |