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Functional Microdomains in Heart’s Pacemaker: A Step Beyond Classical Electrophysiology and Remodeling
Spontaneous beating of the sinoatrial node (SAN), the primary pacemaker of the heart, is initiated, sustained, and regulated by a complex system that integrates ion channels and transporters on the cell membrane surface (often referred to as “membrane clock”) with subcellular calcium handling machin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277479/ https://www.ncbi.nlm.nih.gov/pubmed/30538641 http://dx.doi.org/10.3389/fphys.2018.01686 |