Inositol-Requiring Enzyme 1 Alpha Endoribonuclease Specific Inhibitor STF-083010 Alleviates Carbon Tetrachloride Induced Liver Injury and Liver Fibrosis in Mice

Accumulating data demonstrated that hepatic endoplasmic reticulum (ER) stress was involved in the pathogenesis of liver fibrosis. Long-term chronic hepatocyte death contributed to liver fibrosis initiation and progression. Previous researches reported that ER stress sensor inositol-requiring enzyme...

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Detalles Bibliográficos
Autores principales: Chen, Qian-Qian, Zhang, Cheng, Qin, Ming-Qiang, Li, Jian, Wang, Hua, Xu, De-Xiang, Wang, Jian-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277551/
https://www.ncbi.nlm.nih.gov/pubmed/30538632
http://dx.doi.org/10.3389/fphar.2018.01344

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