Cargando…

Highlights on the Application of Genomics and Bioinformatics in the Fight Against Infectious Diseases: Challenges and Opportunities in Africa

Genomics and bioinformatics are increasingly contributing to our understanding of infectious diseases caused by bacterial pathogens such as Mycobacterium tuberculosis and parasites such as Plasmodium falciparum. This ranges from investigations of disease outbreaks and pathogenesis, host and pathogen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bah, Saikou Y., Morang’a, Collins Misita, Kengne-Ouafo, Jonas A., Amenga–Etego, Lucas, Awandare, Gordon A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277583/ https://www.ncbi.nlm.nih.gov/pubmed/30538723 http://dx.doi.org/10.3389/fgene.2018.00575

Ejemplares similares

Machine learning approaches classify clinical malaria outcomes based on haematological parameters
por: Morang’a, Collins M., et al.
Publicado: (2020)

The global transcriptome of Plasmodium falciparum mid-stage gametocytes (stages II–IV) appears largely conserved and gametocyte-specific gene expression patterns vary in clinical isolates
por: Kengne-Ouafo, Jonas A., et al.
Publicado: (2023)

High-throughput genotyping assays for identification of glycophorin B deletion variants in population studies
por: Amuzu, Dominic SY, et al.
Publicado: (2020)

Prevalence of chloroquine and antifolate drug resistance alleles in Plasmodium falciparum clinical isolates from three areas in Ghana
por: Abugri, James, et al.
Publicado: (2018)

Global Distribution of Founder Variants Associated with Non-Syndromic Hearing Impairment
por: Aboagye, Elvis Twumasi, et al.
Publicado: (2023)

Immune Responses to the Sexual Stages of Plasmodium falciparum Parasites
por: Kengne-Ouafo, Jonas A., et al.
Publicado: (2019)

Age Estimate of GJB2-p.(Arg143Trp) Founder Variant in Hearing Impairment in Ghana, Suggests Multiple Independent Origins across Populations
por: Aboagye, Elvis Twumasi, et al.
Publicado: (2022)

Plasmodium falciparum Malaria Parasites in Ghana Show Signatures of Balancing Selection at Artemisinin Resistance Predisposing Background Genes
por: Tandoh, Kwesi Z, et al.
Publicado: (2021)

Temporal evolution of sulfadoxine-pyrimethamine resistance genotypes and genetic diversity in response to a decade of increased interventions against Plasmodium falciparum in northern Ghana
por: Amenga-Etego, Lucas N., et al.
Publicado: (2021)

Pausing the Fight Against Malaria to Combat the COVID-19 Pandemic in Africa: Is the Future of Malaria Bleak?
por: Nghochuzie, Nora Nganyewo, et al.
Publicado: (2020)

Socio-demographic and environmental determinants of infectious disease morbidity in children under 5 years in Ghana
por: Amugsi, Dickson A., et al.
Publicado: (2015)

Co-infection of Plasmodium falciparum and Schistosoma mansoni is associated with anaemia
por: Dassah, Sylvester Donne, et al.
Publicado: (2023)

Analysis of Plasmodium falciparum Rh2b deletion polymorphism across different transmission areas
por: Aniweh, Yaw, et al.
Publicado: (2020)

Stabilization of RDT target antigens present in dried Plasmodium falciparum-infected samples for validating malaria rapid diagnostic tests at the point of care
por: Morang’a, Collins, et al.
Publicado: (2018)

Comparative Susceptibility of Plasmodium ovale and Plasmodium falciparum Field Isolates to Reference and Lead Candidate Antimalarial Drugs in Ghana
por: Aniweh, Yaw, et al.
Publicado: (2023)

A novel autosomal dominant GREB1L variant associated with non-syndromic hearing impairment in Ghana
por: Adadey, Samuel Mawuli, et al.
Publicado: (2022)

Genomic analysis of SARS-CoV-2 reveals local viral evolution in Ghana
por: Ngoi, Joyce M, et al.
Publicado: (2020)

A longitudinal two-year survey of the prevalence of trypanosomes in domestic cattle in Ghana by massively parallel sequencing of barcoded amplicons
por: Ofori, Jennifer Afua, et al.
Publicado: (2022)

Drug resistance and vaccine target surveillance of Plasmodium falciparum using nanopore sequencing in Ghana
por: Girgis, Sophia T., et al.
Publicado: (2023)

Approaches to estimating inbreeding coefficients in clinical isolates of Plasmodium falciparum from genomic sequence data
por: O’Brien, John D., et al.
Publicado: (2016)

The biology of unconventional invasion of Duffy-negative reticulocytes by Plasmodium vivax and its implication in malaria epidemiology and public health
por: Golassa, Lemu, et al.
Publicado: (2020)

Development of Cooperative Primer-Based Real-Time PCR Assays for the Detection of Plasmodium malariae and Plasmodium ovale
por: Ansah, Felix, et al.
Publicado: (2021)

Inferring Strain Mixture within Clinical Plasmodium falciparum Isolates from Genomic Sequence Data
por: O’Brien, John D., et al.
Publicado: (2016)

Collaboration in the fight against infectious diseases.
por: Shalala, D E
Publicado: (1998)

Antibody Reactivity to Merozoite Antigens in Ghanaian Adults Correlates With Growth Inhibitory Activity Against Plasmodium falciparum in Culture
por: Mensah-Brown, Henrietta E, et al.
Publicado: (2019)

Recent increase in low complexity polygenomic infections and sialic acid-independent invasion pathways in Plasmodium falciparum from Western Gambia
por: Nganyewo, Nora Nghochuzie, et al.
Publicado: (2023)

A Competing Risk Analysis of Women Dying of Maternal, Infectious, or Non-Communicable Causes in the Kintampo Area of Ghana
por: Abubakari, Sulemana Watara, et al.
Publicado: (2021)

Evaluation of a laboratory quality assurance pilot programme for malaria diagnostics in low-transmission areas of Kenya, 2013
por: Wanja, Elizabeth, et al.
Publicado: (2017)

Comparative evaluation of fluorescent in situ hybridization and Giemsa microscopy with quantitative real-time PCR technique in detecting malaria parasites in a holoendemic region of Kenya
por: Osoga, Joseph, et al.
Publicado: (2017)

Highlighting Shooting Opportunities in Football
por: Loutfi, Ilias, et al.
Publicado: (2023)

Portable sequencer in the fight against infectious disease
por: Mongan, Arthur Elia, et al.
Publicado: (2019)

DNA Nanostructures in the Fight Against Infectious Diseases
por: Smith, David M., et al.
Publicado: (2021)

Infectious: Pathogens and How We Fight Them
por: M’ikanatha, Nkuchia M.
Publicado: (2023)

Antimicrobial Peptide Synergies for Fighting Infectious Diseases
por: Mhlongo, Jessica T., et al.
Publicado: (2023)

Porvair highlights its role in supporting the fight against Covid-19
Publicado: (2020)

Regen med therapeutic opportunities for fighting COVID‐19
por: Atala, Anthony, et al.
Publicado: (2020)

Population genetic analysis of the Plasmodium falciparum circumsporozoite protein in two distinct ecological regions in Ghana
por: Amegashie, Elikplim A., et al.
Publicado: (2020)

Nuclear Physics in Europe: Highlights and Opportunities
por: Galès, Sydney, et al.
Publicado: (1997)

A Bayesian Approach to Inferring the Phylogenetic Structure of Communities from Metagenomic Data
por: O’Brien, John D., et al.
Publicado: (2014)

Socio-demographic and behavioural determinants of body mass index among an adult population in rural Northern Ghana: the AWI-Gen study
por: Nonterah, Engelbert Adamwaba, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gj846r1t93pjfcq8hh884jnv8v