Detection of Exon 12 and 14 Mutations in Janus Kinase 2 Gene Including a Novel Mutant in V617F Negative Polycythemia Vera Patients from Pakistan

The most frequently reported genetic aberration among polycythemia vera (PV) patients is a gain of function mutation V617F in exon 14 of Janus kinase 2 (JAK2) gene. However in many investigations, V617F negative PV patients have been reported to harbor mutations in JAK 2 exon 12. We investigated 24...

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Detalles Bibliográficos
Autores principales: Akram, Afia Muhammad, kausar, Humera, Chaudhary, Asma, Khalid, Ahmad Mukhtar, Shahzad, Muhammad Mudassar, Akhtar, Muhammad Waheed, Sabar, Muhammad Farooq, Sajid, Nadia, Anazi, Nawaf Al, Aleem, Aamer, Iqbal, Zafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277640/
https://www.ncbi.nlm.nih.gov/pubmed/30519338
http://dx.doi.org/10.7150/jca.27414

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