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Tenascin-C Modulates Cell Cycle Progression to Enhance Tumour Cell Proliferation through AKT/FOXO1 Signalling in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is a disease with an extremely poor prognosis that is characterized by a rich extracellular matrix (ECM). Tenascin-C (TNC) is a component of the ECM and plays a role in tumour progression. In this study, we reported that TNC is overexpressed in PDAC tissues an...

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Detalles Bibliográficos
Autores principales: Cai, Jun, Lu, Wenli, Du, Shaoxia, Guo, Zhongkui, Wang, Hui, Wei, Wei, Shen, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277647/
https://www.ncbi.nlm.nih.gov/pubmed/30519351
http://dx.doi.org/10.7150/jca.25926

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