Cargando…

Effect of Betahistine and Metformin on Antipsychotic-Induced Weight Gain: An Analysis of Two Clinical Trials

Antipsychotic-induced weight gain is one of the most common adverse effects of antipsychotic treatment. However, there are no well-established interventions for the weight gain yet. In this study, we pooled the data from two clinical trials, which were originally examining the efficacy of betahistin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Dongyu, Jing, Zhihui, Li, Ranran, Hei, Gangrui, Shao, Tiannan, Li, Li, Sun, Mengxi, Yang, Ye, Wang, Ying, Wang, Xiaoyi, Long, Yujun, Huang, Xiansheng, Wu, Renrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277778/ https://www.ncbi.nlm.nih.gov/pubmed/30542300 http://dx.doi.org/10.3389/fpsyt.2018.00620

Ejemplares similares

Optimizing and Individualizing the Pharmacological Treatment of First-Episode Schizophrenic Patients: Study Protocol for a Multicenter Clinical Trial
por: Xiao, Jingmei, et al.
Publicado: (2021)

Metformin improves cognitive impairment in patients with schizophrenia: associated with enhanced functional connectivity of dorsolateral prefrontal cortex
por: Shao, Tiannan, et al.
Publicado: (2023)

The Association Between Antipsychotics and Weight Gain and the Potential Role of Metformin Concomitant Use: A Retrospective Cohort Study
por: Hakami, Alqassem Y., et al.
Publicado: (2022)

The effects of probiotics plus dietary fiber on antipsychotic-induced weight gain: a randomized clinical trial
por: Huang, Jing, et al.
Publicado: (2022)

Efficacy of betahistine in counteracting second-generation antipsychotics-induced weight gain: A meta-analysis with trial sequential analysis
por: Soliman, Y., et al.
Publicado: (2023)

The Burden of Antipsychotic-Induced Weight Gain and Metabolic Syndrome in Children
por: Libowitz, Mark R., et al.
Publicado: (2021)

Antipsychotic-Induced Weight Gain and Clinical Improvement: A Psychiatric Paradox
por: Garcia-Rizo, Clemente
Publicado: (2020)

Commentary: A Randomized, Double-Blind, Placebo-Controlled Trial of Metformin Treatment of Weight Gain Associated with Initiation of Atypical Antipsychotic Therapy in Children and Adolescents
por: Goltz, Jeffrey Samuel, et al.
Publicado: (2017)

The role of metformin in treatment of weight gain associated with atypical antipsychotic treatment in children and adolescents: A systematic review and meta-analysis of randomized controlled trials
por: Mansuri, Zeeshan, et al.
Publicado: (2022)

The potential effect of metformin on cognitive and other symptom dimensions in patients with schizophrenia and antipsychotic-induced weight gain: a systematic review, meta-analysis, and meta-regression
por: Battini, Vera, et al.
Publicado: (2023)

Identifying and revealing different brain neural activities of cognitive subtypes in early course schizophrenia
por: Shao, Tiannan, et al.
Publicado: (2022)

High-Dose Betahistine Improves Cognitive Function in Patients With Schizophrenia: A Randomized Double-Blind Placebo-Controlled Trial
por: Wang, Yongqian, et al.
Publicado: (2021)

A novel transdermal nanoethosomal gel of betahistine dihydrochloride for weight gain control: in-vitro and in-vivo characterization
por: El-Menshawe, Shahira F, et al.
Publicado: (2017)

S2. ANTIPSYCHOTICS RESULT IN WEIGHT GAIN BUT THE SEVERITY OF WEIGHT GAIN DIFFERS BETWEEN ANTIPSYCHOTICS
por: Bak, Maarten, et al.
Publicado: (2020)

Preventing Olanzapine-Induced Weight Gain Using Betahistine: A Study in a Rat Model with Chronic Olanzapine Treatment
por: Lian, Jiamei, et al.
Publicado: (2014)

Metformin in prevention and treatment of antipsychotic induced weight gain: a systematic review and meta-analysis
por: de Silva, Varuni Asanka, et al.
Publicado: (2016)

Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin – a case series
por: Prasad, Femin, et al.
Publicado: (2023)

The Wnt Signaling Pathway Effector TCF7L2 Mediates Olanzapine-Induced Weight Gain and Insulin Resistance
por: Li, Ranran, et al.
Publicado: (2018)

Changes in Brain Structure, Function, and Network Properties in Patients With First-Episode Schizophrenia Treated With Antipsychotics
por: Yin, Ping, et al.
Publicado: (2021)

Bidirectional Causal Connectivity in the Cortico-Limbic-Cerebellar Circuit Related to Structural Alterations in First-Episode, Drug-Naive Somatization Disorder
por: Li, Ranran, et al.
Publicado: (2018)

Metabolic biomarkers of risperidone-induced weight gain in drug-naïve patients with schizophrenia
por: Qiu, Yuying, et al.
Publicado: (2023)

Betahistine in the treatment of Ménière’s disease
por: Lacour, Michel, et al.
Publicado: (2007)

Effects of sulforaphane on cognitive function in patients with frontal brain damage: study protocol for a randomised controlled trial
por: Liu, Fangkun, et al.
Publicado: (2020)

Probiotics Plus Dietary Fiber Supplements Attenuate Olanzapine-Induced Weight Gain in Drug-Naïve First-Episode Schizophrenia Patients: Two Randomized Clinical Trials
por: Huang, Jing, et al.
Publicado: (2022)

Topiramate and Metformin Are Effective Add-On Treatments in Controlling Antipsychotic-Induced Weight Gain: A Systematic Review and Network Meta-Analysis
por: Zhuo, Chuanjun, et al.
Publicado: (2018)

Synergistic Effects of Psychotropics Leading to Extraordinary Weight Gain
por: Kemp, Allyson J, et al.
Publicado: (2021)

Association of MTHFR C677T Polymorphism With Antipsychotic-Induced Change of Weight and Metabolism Index
por: Su, Yi, et al.
Publicado: (2021)

Association between neuropeptide Y gene polymorphism and antipsychotics effect
por: Zhang, Qian, et al.
Publicado: (2022)

Acetazolamide for Antipsychotic-Associated Weight Gain in Schizophrenia
por: Kakunje, Anil, et al.
Publicado: (2018)

Efficacy and Safety of Adjunctive Aripiprazole, Metformin, and Paeoniae–Glycyrrhiza Decoction for Antipsychotic-Induced Hyperprolactinemia: A Network Meta-Analysis of Randomized Controlled Trials
por: Zhang, Ling, et al.
Publicado: (2021)

Influence of Identity Development on Weight Gain in Adolescent Anorexia Nervosa
por: Budde, Lynn I., et al.
Publicado: (2022)

C677T Polymorphism in the MTHFR Gene Is Associated With Risperidone-Induced Weight Gain in Schizophrenia
por: Liao, Jingping, et al.
Publicado: (2020)

Antipsychotics result in more weight gain in antipsychotic naive patients than in patients after antipsychotic switch and weight gain is irrespective of psychiatric diagnosis: A meta-analysis
por: Bak, Maarten, et al.
Publicado: (2021)

Worth the Weight? Olanzapine Prescribing in Schizophrenia. A Review of Weight Gain and Other Cardiometabolic Side Effects of Olanzapine
por: Fitzgerald, Ita, et al.
Publicado: (2021)

Altered gene expression in antipsychotic-induced weight gain
por: Crespo-Facorro, Benedicto, et al.
Publicado: (2019)

Combination approaches to reduce weight-gain induced by antipsychotics
por: Hofer, A.
Publicado: (2021)

Spectrophotometric estimation of betahistine hydrochloride in tablet formulations
por: Kumar, Amit, et al.
Publicado: (2010)

Betahistine in the treatment of tinnitus in patients with vestibular disorders
por: Ganança, Maurício Malavasi, et al.
Publicado: (2015)

Metformin in the management of antipsychotic-induced weight gain in adults with psychosis: development of the first evidence-based guideline using GRADE methodology
por: Fitzgerald, Ita, et al.
Publicado: (2022)

TOX and ADIPOQ Gene Polymorphisms Are Associated with Antipsychotic-Induced Weight Gain in Han Chinese
por: Li, Shen, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hp2la453akmfqn1bgu6p6323oa