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Acute inflammation sensitizes knee-innervating sensory neurons and decreases mouse digging behavior in a TRPV1-dependent manner
Ongoing, spontaneous pain is characteristic of inflammatory joint pain and reduces an individual's quality of life. To understand the neural basis of inflammatory joint pain, we made a unilateral knee injection of complete Freund's adjuvant (CFA) in mice, which reduced their natural diggin...
Autores principales: | Chakrabarti, Sampurna, Pattison, Luke A., Singhal, Kaajal, Hockley, James R.F., Callejo, Gerard, Smith, Ewan St. John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277850/ https://www.ncbi.nlm.nih.gov/pubmed/30240782 http://dx.doi.org/10.1016/j.neuropharm.2018.09.014 |
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