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Comprehensive Profiling and Inheritance Patterns of Metabolites in Foxtail Millet

Metabolomics aims at determining a sample's metabolites profile and hence provides a straight functional statement of an organism's physiological condition. Here, we investigated comprehensive profiling, natural variation and species-specific accumulation of both primary and secondary meta...

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Autores principales: Li, Shuangdong, Dong, Xuekui, Fan, Guangyu, Yang, Qiaofeng, Shi, Jian, Wei, Wei, Zhao, Fang, Li, Ning, Wang, Xiaoming, Wang, Feng, Feng, Xiaolei, Zhang, Xiaolei, Song, Guoliang, Shi, Gaolei, Zhang, Wenying, Qiu, Fengcang, Wang, Dequan, Li, Xinru, Zhang, Yali, Zhao, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277888/
https://www.ncbi.nlm.nih.gov/pubmed/30542359
http://dx.doi.org/10.3389/fpls.2018.01716
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author Li, Shuangdong
Dong, Xuekui
Fan, Guangyu
Yang, Qiaofeng
Shi, Jian
Wei, Wei
Zhao, Fang
Li, Ning
Wang, Xiaoming
Wang, Feng
Feng, Xiaolei
Zhang, Xiaolei
Song, Guoliang
Shi, Gaolei
Zhang, Wenying
Qiu, Fengcang
Wang, Dequan
Li, Xinru
Zhang, Yali
Zhao, Zhihai
author_facet Li, Shuangdong
Dong, Xuekui
Fan, Guangyu
Yang, Qiaofeng
Shi, Jian
Wei, Wei
Zhao, Fang
Li, Ning
Wang, Xiaoming
Wang, Feng
Feng, Xiaolei
Zhang, Xiaolei
Song, Guoliang
Shi, Gaolei
Zhang, Wenying
Qiu, Fengcang
Wang, Dequan
Li, Xinru
Zhang, Yali
Zhao, Zhihai
author_sort Li, Shuangdong
collection PubMed
description Metabolomics aims at determining a sample's metabolites profile and hence provides a straight functional statement of an organism's physiological condition. Here, we investigated comprehensive profiling, natural variation and species-specific accumulation of both primary and secondary metabolites in foxtail millet using LC-MS, and inheritance patterns of metabolome in millet hybrids. The application of a broad target metabolomics method facilitated the simultaneous identification and quantification of more than 300 metabolites. The metabolic analysis of these compounds, such as flavonoids, phenolamides, hydrocinnamoyl derivatives, vitamins and LPCs, revealed their developmentally controlled accumulation, and natural variation in different tissues/varieties. Species-specific accumulation of secondary metabolites was observed based on a comparative metabolic analysis between millet and rice, such as flavonoid O-rutinosides/neohesperidosides and malonylated flavonoid O-glycosides. In analyzing the metabolic variations between hybrid progenies and their parental lines, including a photothermo-sensitive genic male sterility line and five Zhangzagu varieties, metabolic overdominant, and dominant patterns of inheritance could be observed. For example, hydrocinnamoyl derivatives and feruloylated flavonoids were identified as over-parent heterosis (overdominant) metabolites in milet hybrids. Our work paves the way for developing predictors of hybrid performance and the future analysis of the biosynthesis and regulation of relevant metabolic pathways in millet.
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spelling pubmed-62778882018-12-12 Comprehensive Profiling and Inheritance Patterns of Metabolites in Foxtail Millet Li, Shuangdong Dong, Xuekui Fan, Guangyu Yang, Qiaofeng Shi, Jian Wei, Wei Zhao, Fang Li, Ning Wang, Xiaoming Wang, Feng Feng, Xiaolei Zhang, Xiaolei Song, Guoliang Shi, Gaolei Zhang, Wenying Qiu, Fengcang Wang, Dequan Li, Xinru Zhang, Yali Zhao, Zhihai Front Plant Sci Plant Science Metabolomics aims at determining a sample's metabolites profile and hence provides a straight functional statement of an organism's physiological condition. Here, we investigated comprehensive profiling, natural variation and species-specific accumulation of both primary and secondary metabolites in foxtail millet using LC-MS, and inheritance patterns of metabolome in millet hybrids. The application of a broad target metabolomics method facilitated the simultaneous identification and quantification of more than 300 metabolites. The metabolic analysis of these compounds, such as flavonoids, phenolamides, hydrocinnamoyl derivatives, vitamins and LPCs, revealed their developmentally controlled accumulation, and natural variation in different tissues/varieties. Species-specific accumulation of secondary metabolites was observed based on a comparative metabolic analysis between millet and rice, such as flavonoid O-rutinosides/neohesperidosides and malonylated flavonoid O-glycosides. In analyzing the metabolic variations between hybrid progenies and their parental lines, including a photothermo-sensitive genic male sterility line and five Zhangzagu varieties, metabolic overdominant, and dominant patterns of inheritance could be observed. For example, hydrocinnamoyl derivatives and feruloylated flavonoids were identified as over-parent heterosis (overdominant) metabolites in milet hybrids. Our work paves the way for developing predictors of hybrid performance and the future analysis of the biosynthesis and regulation of relevant metabolic pathways in millet. Frontiers Media S.A. 2018-11-26 /pmc/articles/PMC6277888/ /pubmed/30542359 http://dx.doi.org/10.3389/fpls.2018.01716 Text en Copyright © 2018 Li, Dong, Fan, Yang, Shi, Wei, Zhao, Li, Wang, Wang, Feng, Zhang, Song, Shi, Zhang, Qiu, Wang, Li, Zhang and Zhao. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Li, Shuangdong
Dong, Xuekui
Fan, Guangyu
Yang, Qiaofeng
Shi, Jian
Wei, Wei
Zhao, Fang
Li, Ning
Wang, Xiaoming
Wang, Feng
Feng, Xiaolei
Zhang, Xiaolei
Song, Guoliang
Shi, Gaolei
Zhang, Wenying
Qiu, Fengcang
Wang, Dequan
Li, Xinru
Zhang, Yali
Zhao, Zhihai
Comprehensive Profiling and Inheritance Patterns of Metabolites in Foxtail Millet
title Comprehensive Profiling and Inheritance Patterns of Metabolites in Foxtail Millet
title_full Comprehensive Profiling and Inheritance Patterns of Metabolites in Foxtail Millet
title_fullStr Comprehensive Profiling and Inheritance Patterns of Metabolites in Foxtail Millet
title_full_unstemmed Comprehensive Profiling and Inheritance Patterns of Metabolites in Foxtail Millet
title_short Comprehensive Profiling and Inheritance Patterns of Metabolites in Foxtail Millet
title_sort comprehensive profiling and inheritance patterns of metabolites in foxtail millet
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277888/
https://www.ncbi.nlm.nih.gov/pubmed/30542359
http://dx.doi.org/10.3389/fpls.2018.01716
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