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Sulforaphane Inhibited the Nociceptive Responses, Anxiety- and Depressive-Like Behaviors Associated With Neuropathic Pain and Improved the Anti-allodynic Effects of Morphine in Mice
Chronic neuropathic pain is associated with anxiety- and depressive-like disorders. Its treatment remains a serious clinical problem due to the lack of efficacy of the available therapeutic modalities. We investigated if the activation of the transcription factor Nrf2 could modulate the nociceptive...
Autores principales: | Ferreira-Chamorro, Pablo, Redondo, Alejandro, Riego, Gabriela, Leánez, Sergi, Pol, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277937/ https://www.ncbi.nlm.nih.gov/pubmed/30542282 http://dx.doi.org/10.3389/fphar.2018.01332 |
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