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In vitro effects of levosimendan on muscle of malignant hyperthermia susceptible and non-susceptible swine

BACKGROUND: The calcium sensitizer levosimendan is increasingly used to improve hemodynamics in patients with acutely decompensated heart failure. By binding to cardiac troponin C the conformation of the calcium-troponin C complex is stabilized, which leads to acceleration of actin-myosin crossbrigd...

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Detalles Bibliográficos
Autores principales: Schuster, Frank, Johannsen, Stephan, Isbary, Susanne, Türkmeneli, Ismail, Roewer, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278068/
https://www.ncbi.nlm.nih.gov/pubmed/30509180
http://dx.doi.org/10.1186/s12871-018-0644-z