Mutated Von Hippel-Lindau-renal cell carcinoma (RCC) promotes patients specific natural killer (NK) cytotoxicity

BACKGROUND: Previous evidence demonstrated that restoration of wild type VHL in human renal cancer cells decreased in vitro NK susceptibility. To investigate on the role of tumoral VHL status versus NK capability in renal cancer patients, 51 RCC patients were characterized for VHL mutational status...

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Detalles Bibliográficos
Autores principales: Trotta, Anna Maria, Santagata, Sara, Zanotta, Serena, D’Alterio, Crescenzo, Napolitano, Maria, Rea, Giuseppina, Camerlingo, Rosa, Esposito, Fabio, Lamantia, Elvira, Anniciello, Annamaria, Botti, Giovanni, Longo, Nicola, Botti, Gerardo, Pignata, Sandro, Perdonà, Sisto, Scala, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278085/
https://www.ncbi.nlm.nih.gov/pubmed/30514329
http://dx.doi.org/10.1186/s13046-018-0952-7

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