The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway

BACKGROUND: Peritoneal dissemination is a critical prognostic factor in ovarian cancer. Although stabilized spheroid formation promotes cancer cell peritoneal dissemination in ovarian cancer, the associated oncogenes are unknown. In this study, we assessed the role of the KRAS oncogene in ovarian ca...

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Detalles Bibliográficos
Autores principales: Ogishima, Juri, Taguchi, Ayumi, Kawata, Akira, Kawana, Kei, Yoshida, Mitsuyo, Yoshimatsu, Yuki, Sato, Masakazu, Nakamura, Hiroe, Kawata, Yoshiko, Nishijima, Akira, Fujimoto, Asaha, Tomio, Kensuke, Adachi, Katsuyuki, Nagamatsu, Takeshi, Oda, Katsutoshi, Kiyono, Tohru, Osuga, Yutaka, Fujii, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278087/
https://www.ncbi.nlm.nih.gov/pubmed/30509235
http://dx.doi.org/10.1186/s12885-018-4922-4

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