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Comprehensive methylation analysis of imprinting-associated differentially methylated regions in colorectal cancer
BACKGROUND: Imprinted genes are regulated by DNA methylation at imprinting-associated differentially methylated regions (iDMRs). Abnormal expression of imprinted genes is implicated in imprinting disorders and tumors. In colorectal cancer (CRC), methylation and imprinting status of the IGF2/H19 doma...
Autores principales: | Hidaka, Hidenori, Higashimoto, Ken, Aoki, Saori, Mishima, Hiroyuki, Hayashida, Chisa, Maeda, Toshiyuki, Koga, Yasuo, Yatsuki, Hitomi, Joh, Keiichiro, Noshiro, Hirokazu, Iwakiri, Ryuichi, Kawaguchi, Atsushi, Yoshiura, Koh-ichiro, Fujimoto, Kazuma, Soejima, Hidenobu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278095/ https://www.ncbi.nlm.nih.gov/pubmed/30509319 http://dx.doi.org/10.1186/s13148-018-0578-9 |
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