Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease

OBJECTIVE: To identify genetic variation influencing late-onset Alzheimer disease (LOAD), we used a large data set of non-Hispanic white (NHW) extended families multiply-affected by LOAD by performing whole genome sequencing (WGS). METHODS: As part of the Alzheimer Disease Sequencing Project, WGS da...

Descripción completa

Detalles Bibliográficos
Autores principales: Beecham, Gary W., Vardarajan, Badri, Blue, Elizabeth, Bush, William, Jaworski, James, Barral, Sandra, DeStefano, Anita, Hamilton-Nelson, Kara, Kunkle, Brian, Martin, Eden R., Naj, Adam, Rajabli, Farid, Reitz, Christiane, Thornton, Timothy, van Duijn, Cornelia, Goate, Allison, Seshadri, Sudha, Farrer, Lindsay A., Boerwinkle, Eric, Schellenberg, Gerard, Haines, Jonathan L., Wijsman, Ellen, Mayeux, Richard, Pericak-Vance, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278241/
https://www.ncbi.nlm.nih.gov/pubmed/30569016
http://dx.doi.org/10.1212/NXG.0000000000000286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278241/
https://www.ncbi.nlm.nih.gov/pubmed/30569016
http://dx.doi.org/10.1212/NXG.0000000000000286

Ejemplares similares