A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions

A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-b]pyrrole and acenaphtho[1,2-b]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The signifi...

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Detalles Bibliográficos
Autores principales: Tang, Xiaodong, Zhu, Songlei, Ma, Ying, Wen, Ren, Cen, Lanqi, Gong, Panwei, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278260/
https://www.ncbi.nlm.nih.gov/pubmed/30463337
http://dx.doi.org/10.3390/molecules23113031
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author Tang, Xiaodong
Zhu, Songlei
Ma, Ying
Wen, Ren
Cen, Lanqi
Gong, Panwei
Wang, Jing
author_facet Tang, Xiaodong
Zhu, Songlei
Ma, Ying
Wen, Ren
Cen, Lanqi
Gong, Panwei
Wang, Jing
author_sort Tang, Xiaodong
collection PubMed
description A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-b]pyrrole and acenaphtho[1,2-b]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The significant features of this procedure were characterized by mild reaction conditions, high yields, operational simplicity and it being environmentally benign.
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spelling pubmed-62782602018-12-13 A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions Tang, Xiaodong Zhu, Songlei Ma, Ying Wen, Ren Cen, Lanqi Gong, Panwei Wang, Jing Molecules Article A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-b]pyrrole and acenaphtho[1,2-b]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The significant features of this procedure were characterized by mild reaction conditions, high yields, operational simplicity and it being environmentally benign. MDPI 2018-11-20 /pmc/articles/PMC6278260/ /pubmed/30463337 http://dx.doi.org/10.3390/molecules23113031 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tang, Xiaodong
Zhu, Songlei
Ma, Ying
Wen, Ren
Cen, Lanqi
Gong, Panwei
Wang, Jing
A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions
title A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions
title_full A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions
title_fullStr A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions
title_full_unstemmed A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions
title_short A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions
title_sort simple and efficient synthesis of highly substituted indeno[1,2-b]pyrrole and acenaphtho[1,2-b]pyrrole derivatives by tandem three-component reactions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278260/
https://www.ncbi.nlm.nih.gov/pubmed/30463337
http://dx.doi.org/10.3390/molecules23113031
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