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Quinazolin-4(3H)-ones and 5,6-Dihydropyrimidin-4(3H)-ones from β-Aminoamides and Orthoesters

Quinazolin-4(3H)-ones have been prepared in one step from 2-aminobenzamides and orthoesters in the presence of acetic acid. Simple 2-aminobenzamides were easily converted to the heterocycles by refluxing in absolute ethanol with 1.5 equivalents of the orthoester and 2 equivalents of acetic acid for...

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Detalles Bibliográficos
Autores principales: Gavin, Joshua T., Annor-Gyamfi, Joel K., Bunce, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278269/
https://www.ncbi.nlm.nih.gov/pubmed/30423947
http://dx.doi.org/10.3390/molecules23112925

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