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Synthesis and Evaluation of Anticancer Activities of Novel C-28 Guanidine-Functionalized Triterpene Acid Derivatives

Triterpene acids, namely, 20,29-dihydrobetulinic acid (BA), ursolic acid (UA) and oleanolic acid (OA) were converted into C-28-amino-functionalized triterpenoids 4–7, 8a, 15, 18 and 20. These compounds served as precursors for the synthesis of novel guanidine-functionalized triterpene acid derivativ...

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Detalles Bibliográficos
Autores principales: Spivak, Anna, Khalitova, Rezeda, Nedopekina, Darya, Dzhemileva, Lilya, Yunusbaeva, Milyausha, Odinokov, Victor, D’yakonov, Vladimir, Dzhemilev, Usein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278366/
https://www.ncbi.nlm.nih.gov/pubmed/30453551
http://dx.doi.org/10.3390/molecules23113000