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Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer
Pancreatic cancer (PC) is a lethal solid malignancy with resistance to traditional chemotherapy. Recently, considerable studies have demonstrated the ubiquitous antitumor properties of gene therapy mediated by the oncolytic vaccinia virus. The second mitochondrial-derived activator of caspase (Smac)...
Autores principales: | Chen, Wanyuan, Fan, Weimin, Ru, Guoqing, Huang, Fang, Lu, Xiaming, Zhang, Xin, Mou, Xiaozhou, Wang, Shibing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278373/ https://www.ncbi.nlm.nih.gov/pubmed/30365143 http://dx.doi.org/10.3892/or.2018.6817 |
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