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Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives

Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal che...

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Detalles Bibliográficos
Autores principales: Zhang, Shu-Guang, Liang, Chao-Gen, Zhang, Wei-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278422/
https://www.ncbi.nlm.nih.gov/pubmed/30373212
http://dx.doi.org/10.3390/molecules23112783
Descripción
Sumario:Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal chemistry. This review aims to summarize the recent advances in various methods for the synthesis of indazole derivatives. The current developments in the biological activities of indazole-based compounds are also presented.