Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives

Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal che...

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Autores principales: Zhang, Shu-Guang, Liang, Chao-Gen, Zhang, Wei-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278422/
https://www.ncbi.nlm.nih.gov/pubmed/30373212
http://dx.doi.org/10.3390/molecules23112783
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author Zhang, Shu-Guang
Liang, Chao-Gen
Zhang, Wei-Hua
author_facet Zhang, Shu-Guang
Liang, Chao-Gen
Zhang, Wei-Hua
author_sort Zhang, Shu-Guang
collection PubMed
description Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal chemistry. This review aims to summarize the recent advances in various methods for the synthesis of indazole derivatives. The current developments in the biological activities of indazole-based compounds are also presented.
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spelling pubmed-62784222018-12-13 Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives Zhang, Shu-Guang Liang, Chao-Gen Zhang, Wei-Hua Molecules Review Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal chemistry. This review aims to summarize the recent advances in various methods for the synthesis of indazole derivatives. The current developments in the biological activities of indazole-based compounds are also presented. MDPI 2018-10-26 /pmc/articles/PMC6278422/ /pubmed/30373212 http://dx.doi.org/10.3390/molecules23112783 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Shu-Guang
Liang, Chao-Gen
Zhang, Wei-Hua
Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives
title Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives
title_full Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives
title_fullStr Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives
title_full_unstemmed Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives
title_short Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives
title_sort recent advances in indazole-containing derivatives: synthesis and biological perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278422/
https://www.ncbi.nlm.nih.gov/pubmed/30373212
http://dx.doi.org/10.3390/molecules23112783
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