Imidazo[1,2-b]pyrazole-7-carboxamides Induce Apoptosis in Human Leukemia Cells at Nanomolar Concentrations

Leukemia, the malignancy of the hematopoietic system accounts for 10% of cancer cases with poor overall survival rate in adults; therefore, there is a high unmet medical need for the development of novel therapeutics. Eight imidazo[1,2-b]pyrazole-7-carboxamides have been tested for cytotoxic activit...

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Detalles Bibliográficos
Autores principales: Szebeni, Gábor J., Balog, József A., Demjén, András, Alföldi, Róbert, Végi, Vanessza L., Fehér, Liliána Z., Mán, Imola, Kotogány, Edit, Gubán, Barbara, Batár, Péter, Hackler, László, Kanizsai, Iván, Puskás, László G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278434/
https://www.ncbi.nlm.nih.gov/pubmed/30388846
http://dx.doi.org/10.3390/molecules23112845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278434/
https://www.ncbi.nlm.nih.gov/pubmed/30388846
http://dx.doi.org/10.3390/molecules23112845

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