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Imidazo[1,2-b]pyrazole-7-carboxamides Induce Apoptosis in Human Leukemia Cells at Nanomolar Concentrations
Leukemia, the malignancy of the hematopoietic system accounts for 10% of cancer cases with poor overall survival rate in adults; therefore, there is a high unmet medical need for the development of novel therapeutics. Eight imidazo[1,2-b]pyrazole-7-carboxamides have been tested for cytotoxic activit...
Autores principales: | Szebeni, Gábor J., Balog, József A., Demjén, András, Alföldi, Róbert, Végi, Vanessza L., Fehér, Liliána Z., Mán, Imola, Kotogány, Edit, Gubán, Barbara, Batár, Péter, Hackler, László, Kanizsai, Iván, Puskás, László G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278434/ https://www.ncbi.nlm.nih.gov/pubmed/30388846 http://dx.doi.org/10.3390/molecules23112845 |
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