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The Development of Assays for Heparanase Enzymatic Activity: Towards a Gold Standard
The enzyme heparanase, an endo-β-glucuronidase, degrades heparan sulfate (HS) chains on the cell surface and in the extracellular matrix. Heparanase regulates numerous biological processes that drive tumour growth, metastasis and angiogenesis. In addition to its key role in cancer progression, it ha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278452/ https://www.ncbi.nlm.nih.gov/pubmed/30441818 http://dx.doi.org/10.3390/molecules23112971 |