Identification of a 2′-O-Methyluridine Nucleoside Hydrolase Using the Metagenomic Libraries

Ribose methylation is among the most ubiquitous modifications found in RNA. 2′-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota. Moreover, 2′-O-methylribonucleosides are promising starting materials for the production of nucleic acid-based drugs. Despite t...

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Detalles Bibliográficos
Autores principales: Aučynaitė, Agota, Rutkienė, Rasa, Tauraitė, Daiva, Meškys, Rolandas, Urbonavičius, Jaunius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278475/
https://www.ncbi.nlm.nih.gov/pubmed/30405065
http://dx.doi.org/10.3390/molecules23112904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278475/
https://www.ncbi.nlm.nih.gov/pubmed/30405065
http://dx.doi.org/10.3390/molecules23112904

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