An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction

A concise and efficient synthesis of acenaphtho[1,2-b]indole derivatives via the domino reactions of enaminones with acenaphthoquinone catalyzed by l-proline has been developed. This protocol has the advantages of good yields, operational convenience and high regioselectivity.

Detalles Bibliográficos
Autores principales: Zhang, Guo-Ning, Yuan, Xia, Niu, Weiping, Zhu, Mei, Wang, Juxian, Wang, Yucheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278500/
https://www.ncbi.nlm.nih.gov/pubmed/30469372
http://dx.doi.org/10.3390/molecules23113045
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author Zhang, Guo-Ning
Yuan, Xia
Niu, Weiping
Zhu, Mei
Wang, Juxian
Wang, Yucheng
author_facet Zhang, Guo-Ning
Yuan, Xia
Niu, Weiping
Zhu, Mei
Wang, Juxian
Wang, Yucheng
author_sort Zhang, Guo-Ning
collection PubMed
description A concise and efficient synthesis of acenaphtho[1,2-b]indole derivatives via the domino reactions of enaminones with acenaphthoquinone catalyzed by l-proline has been developed. This protocol has the advantages of good yields, operational convenience and high regioselectivity.
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spelling pubmed-62785002018-12-13 An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction Zhang, Guo-Ning Yuan, Xia Niu, Weiping Zhu, Mei Wang, Juxian Wang, Yucheng Molecules Article A concise and efficient synthesis of acenaphtho[1,2-b]indole derivatives via the domino reactions of enaminones with acenaphthoquinone catalyzed by l-proline has been developed. This protocol has the advantages of good yields, operational convenience and high regioselectivity. MDPI 2018-11-21 /pmc/articles/PMC6278500/ /pubmed/30469372 http://dx.doi.org/10.3390/molecules23113045 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Guo-Ning
Yuan, Xia
Niu, Weiping
Zhu, Mei
Wang, Juxian
Wang, Yucheng
An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction
title An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction
title_full An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction
title_fullStr An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction
title_full_unstemmed An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction
title_short An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction
title_sort efficient synthesis of acenaphtho[1,2-b]indole derivatives via domino reaction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278500/
https://www.ncbi.nlm.nih.gov/pubmed/30469372
http://dx.doi.org/10.3390/molecules23113045
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