Cargando…

Ultrasound-Assisted Metal-Mediated Method for the Formation of Tetrahydro-3,3′-Disubstituted Biscoumarins

A new method for faster and simple preparation of 3,3′,4,4′-tetrahydro-3,3′-disubstituted-4,4′-biscoumarins with participation of an organozinc reagent is reported. The reaction is promoted by ultrasound irradiation and it offers a simple experimental setup and excellent reproducibility of the resul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koleva, Ana I., Petkova-Yankova, Nevena I., Nikolova, Rositca D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278503/ https://www.ncbi.nlm.nih.gov/pubmed/30380675 http://dx.doi.org/10.3390/molecules23112810

Ejemplares similares

Synthesis and Chemical Properties of 3-Phosphono-coumarins and 1,2-Benzoxaphosphorins as Precursors for Bioactive Compounds
por: Koleva, Ana I., et al.
Publicado: (2019)

A New and Efficient Method for the Synthesis of 3,4-Disubstituted Pyrrolidine-2,5-diones
por: Ilieva, Eleonora D., et al.
Publicado: (2012)

Experimental and Theoretical Study on the Homodimerization Mechanism of 3-Acetylcoumarin
por: Simeonova, Kristina B., et al.
Publicado: (2022)

Efficient Synthesis of Fluorescent Coumarins and Phosphorous-Containing Coumarin-Type Heterocycles via Palladium Catalyzed Cross-Coupling Reactions
por: Lyapchev, Rumen, et al.
Publicado: (2022)

Dialkylation of Indoles with Trichloroacetimidates to Access 3,3-Disubstituted Indolenines
por: Suzuki, Tamie, et al.
Publicado: (2019)

Antibacterial and Antitumor Activities of Biscoumarin and Dihydropyran Derivatives
por: Sui, Yun-Peng, et al.
Publicado: (2015)

Access to 3,3-disubstituted oxindoles via microwave-assisted Cannizzaro and aldol reactions of formaldehyde with isatins and their imines
por: Huang, Xuan, et al.
Publicado: (2021)

Synthesis of Biscoumarin and Dihydropyran Derivatives and Evaluation of Their Antibacterial Activity
por: Li, Jing, et al.
Publicado: (2015)

Synthesis of 3,3-Disubstituted Heterocycles by Pd-Catalyzed Arylallylation of Unactivated Alkenes
por: Phillips, David, et al.
Publicado: (2018)

Copper‐Catalyzed Enantio‐ and Diastereoselective Addition of Silicon Nucleophiles to 3,3‐Disubstituted Cyclopropenes
por: Zhang, Liangliang, et al.
Publicado: (2019)

Structural Basis of Binding and Rationale for the Potent Urease Inhibitory Activity of Biscoumarins
por: Lodhi, Muhammad Arif, et al.
Publicado: (2014)

Facile Synthesis, Characterization, and In Vitro Antimicrobial and Anticancer Activities of Biscoumarin Copolyester Bearing Pendant 3-(Trifluoromethyl)Styrene
por: Kandaswamy, Narendran, et al.
Publicado: (2014)

Ascorbic Acid-Initiated Tandem Radical Cyclization of N-Arylacrylamides to Give 3,3-Disubstituted Oxindoles
por: Liu, Sheng, et al.
Publicado: (2015)

Cross-Cyclotrimerization with Two Nitriles as a Synthetic Pathway to Unsymmetrically 3,3’-Disubstituted bis(Tetrahydroisoquinolines)
por: Kadlčíková, Aneta, et al.
Publicado: (2009)

An Entry to Enantioenriched 3,3-Disubstituted Phthalides through Asymmetric Phase-Transfer-Catalyzed γ-Alkylation
por: Sicignano, Marina, et al.
Publicado: (2020)

New solid phase methodology for the synthesis of biscoumarin derivatives: experimental and in silico approaches
por: Zarenezhad, Elham, et al.
Publicado: (2022)

Asymmetric Ugi 3CR on isatin-derived ketimine: synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives
por: Lesma, Giordano, et al.
Publicado: (2014)

Polarized, V-Shaped, and Conjoined Biscoumarins: From Lack of Dipole Moment Alignment to High Brightness
por: Kielesiński, Łukasz, et al.
Publicado: (2022)

Designing Potent α-Glucosidase Inhibitors: A Synthesis and QSAR Modeling Approach for Biscoumarin Derivatives
por: Phan, Thi-Hong-Truc, et al.
Publicado: (2023)

Regio- and Stereoselective [2+2] Photodimerization of 3-Substituted 2-Alkoxy-2-oxo-2H-1,2-benzoxaphosphorines
por: Nikolova, Rositca D., et al.
Publicado: (2002)

New Biscoumarin Derivatives: Synthesis, Crystal Structure, Theoretical Study and Antibacterial Activity against Staphylococcus aureus
por: Qu, Di, et al.
Publicado: (2014)

Chiral Phase Transfer Catalysis in the Asymmetric Synthesis of a 3,3-Disubstituted Isoindolinone and Determination of Its Absolute Configuration by VCD Spectroscopy
por: Monaco, Guglielmo, et al.
Publicado: (2020)

Reproductive Capacity and Scanning Electron Microscopy (SEM) Analyses of the Micromorphological Surfaces of Three Endemic Satureja Species from Bulgaria
por: Semerdjieva, Ivanka, et al.
Publicado: (2023)

Rhodium-Catalyzed Synthesis of 2,3-Disubstituted Indoles from β,β-Disubstituted Stryryl Azides**
por: Sun, Ke, et al.
Publicado: (2011)

Three-component microwave-assisted synthesis of 3,5-disubstituted pyrazolo[3,4-d]pyrimidin-4-ones
por: Ng, Jia Hui, et al.
Publicado: (2022)

1-Methyl-3-p-tolyl-3,3a,4,9b-tetrahydro-1H-chromeno[4,3-c]isoxazole-3a-carbonitrile
por: Gangadharan, Rajeswari, et al.
Publicado: (2011)

4-(3-Phenyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl)benzenesulfonamide ethanol monosolvate
por: Asiri, Abdullah M., et al.
Publicado: (2012)

Metal-free one-pot synthesis of 2-substituted and 2,3-disubstituted morpholines from aziridines
por: Sun, Hongnan, et al.
Publicado: (2015)

Literature Survey and Further Studies on the 3-Alkylation of N-Unprotected 3-Monosubstituted Oxindoles. Practical Synthesis of N-Unprotected 3,3-Disubstituted Oxindoles and Subsequent Transformations on the Aromatic Ring
por: Kókai, Eszter, et al.
Publicado: (2016)

Organocatalysed one-pot three component synthesis of 3,3′-disubstituted oxindoles featuring an all-carbon quaternary center and spiro[2H-pyran-3,4′-indoline]
por: Nichinde, Chandrakant B., et al.
Publicado: (2023)

SnO(2) nanoparticles: A recyclable and heterogeneous catalyst for Pechmann condensation of coumarins and Knoevenagel condensation–Michael addition of biscoumarins
por: Rangraz, Yalda, et al.
Publicado: (2023)

1-Methyl-3-(naphthalen-1-yl)-3,3a,4,9b-tetrahydro-1H-chromeno[4,3-c]isoxazole-3a-carbonitrile
por: Gangadharan, Rajeswari, et al.
Publicado: (2011)

3-(3-Chlorophenyl)-1-methyl-3,3a,4,9b-tetrahydro-1H-chromeno[4,3-c]isoxazole-3a-carbonitrile
por: Swaminathan, K., et al.
Publicado: (2011)

Mg(3)N(2)-assisted one-pot synthesis of 1,3-disubstituted imidazo[1,5-a]pyridine
por: Patil, Suhas G., et al.
Publicado: (2020)

7-Bromo-4-(7-bromo-3,3-dimethyl-1-oxo-2,3,4,9-tetrahydro-1H-xanthen-9-yl)-3,3-dimethyl-2,3-dihydroxanthen-1(4H)-one ethanol solvate
por: Lian, Chaomei, et al.
Publicado: (2009)

Simple two-step synthesis of 2,4-disubstituted pyrroles and 3,5-disubstituted pyrrole-2-carbonitriles from enones
por: Kucukdisli, Murat, et al.
Publicado: (2014)

Tyrosol Derivatives, Bearing 3,5-Disubstituted Isoxazole and 1,4-Disubstituted Triazole, as Potential Antileukemia Agents by Promoting Apoptosis
por: Abdelkafi-Koubaa, Zaineb, et al.
Publicado: (2022)

rac-6-Ethoxy-3,3a,4,9b-tetrahydro-1,3-diphenyl-1H-chromeno[4,3-c]isoxazole-3a-carbonitrile
por: Paramasivam, S., et al.
Publicado: (2012)

Maternal 3,3’-Diiodothyronine Sulfate Formation from Guinea Pig Placenta Perfused with 3,3’,5-Triodothyronine
por: Wu, Sing-yung, et al.
Publicado: (2021)

Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells
por: Hudáčová, Monika, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b93kbtv9nhbu0vgk2kf3f6qap7