Concise Synthesis of (+)-β- and γ-Apopicropodophyllins, and Dehydrodesoxypodophyllotoxin

Herein, we present an expeditous synthesis of bioactive aryldihydronaphthalene lignans (+)-β- and γ-apopicropodophyllins, and arylnaphthalene lignan dehydrodesoxypodophyllotoxin. The key reaction is regiocontrolled oxidations of stereodivergent aryltetralin lactones, which were easily accessed from...

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Detalles Bibliográficos
Autores principales: Xiao, Jian, Nan, Guangming, Wang, Ya-Wen, Peng, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278515/
https://www.ncbi.nlm.nih.gov/pubmed/30469319
http://dx.doi.org/10.3390/molecules23113037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278515/
https://www.ncbi.nlm.nih.gov/pubmed/30469319
http://dx.doi.org/10.3390/molecules23113037

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