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Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes
1-(p-Methoxyphenyl)tetrazolyl-substituted 6,7-dimethoxy(6,7-methylenedioxy)-1,2,3,4-tetrahydroisoquinolines formed tetrazolyl-substituted azocines in high yields by using activated alkynes. Unsubstituted at 6,7,8-aromatic fragment 1-tetrazolylisoquinoline interacted in several pathways forming tetra...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278526/ https://www.ncbi.nlm.nih.gov/pubmed/30453635 http://dx.doi.org/10.3390/molecules23113010 |
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| author | Titov, Alexander A. Samavati, Reza Alexandrova, Elena V. Borisova, Tatiana N. Dang Thi, Tuyet Anh Nguyen, Van Tuyen Le, Tuan Anh Varlamov, Alexey V. Van der Eycken, Erik V. Voskressensky, Leonid G. |
| author_facet | Titov, Alexander A. Samavati, Reza Alexandrova, Elena V. Borisova, Tatiana N. Dang Thi, Tuyet Anh Nguyen, Van Tuyen Le, Tuan Anh Varlamov, Alexey V. Van der Eycken, Erik V. Voskressensky, Leonid G. |
| author_sort | Titov, Alexander A. |
| collection | PubMed |
| description | 1-(p-Methoxyphenyl)tetrazolyl-substituted 6,7-dimethoxy(6,7-methylenedioxy)-1,2,3,4-tetrahydroisoquinolines formed tetrazolyl-substituted azocines in high yields by using activated alkynes. Unsubstituted at 6,7,8-aromatic fragment 1-tetrazolylisoquinoline interacted in several pathways forming tetrazolyl-substituted azocines, 1-tetrazolyl-1-R-vinylisoquinolines and 3-azaspiro[5.5]undeca-1,7,9-triene. |
| format | Online Article Text |
| id | pubmed-6278526 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-62785262018-12-13 Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes Titov, Alexander A. Samavati, Reza Alexandrova, Elena V. Borisova, Tatiana N. Dang Thi, Tuyet Anh Nguyen, Van Tuyen Le, Tuan Anh Varlamov, Alexey V. Van der Eycken, Erik V. Voskressensky, Leonid G. Molecules Article 1-(p-Methoxyphenyl)tetrazolyl-substituted 6,7-dimethoxy(6,7-methylenedioxy)-1,2,3,4-tetrahydroisoquinolines formed tetrazolyl-substituted azocines in high yields by using activated alkynes. Unsubstituted at 6,7,8-aromatic fragment 1-tetrazolylisoquinoline interacted in several pathways forming tetrazolyl-substituted azocines, 1-tetrazolyl-1-R-vinylisoquinolines and 3-azaspiro[5.5]undeca-1,7,9-triene. MDPI 2018-11-17 /pmc/articles/PMC6278526/ /pubmed/30453635 http://dx.doi.org/10.3390/molecules23113010 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Titov, Alexander A. Samavati, Reza Alexandrova, Elena V. Borisova, Tatiana N. Dang Thi, Tuyet Anh Nguyen, Van Tuyen Le, Tuan Anh Varlamov, Alexey V. Van der Eycken, Erik V. Voskressensky, Leonid G. Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes |
| title | Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes |
| title_full | Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes |
| title_fullStr | Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes |
| title_full_unstemmed | Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes |
| title_short | Synthesis of 1-(para-methoxyphenyl)tetrazolyl-Substituted 1,2,3,4-Tetrahydroisoquinolines and Their Transformations Involving Activated Alkynes |
| title_sort | synthesis of 1-(para-methoxyphenyl)tetrazolyl-substituted 1,2,3,4-tetrahydroisoquinolines and their transformations involving activated alkynes |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278526/ https://www.ncbi.nlm.nih.gov/pubmed/30453635 http://dx.doi.org/10.3390/molecules23113010 |
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