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Discovery of 3-Amino-2-Hydroxypropoxyisoflavone Derivatives as Potential Anti-HCV Agents

Synthesis and anti-hepatitis C virus (anti-HCV) effects of certain 3-amino-2-hydroxy-propoxy isoflavone derivatives, 6a–i, were described. The known 3-(3,4-dimethoxyphenyl)-7-(oxiran-2-ylmethoxy)-4H-chromen-4-one (5) was reacted with substituted amines to give the desired isoflavone derivatives, 6a–...

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Detalles Bibliográficos
Autores principales:	Lee, Jin-Ching, Lin, Chun-Kuang, Tseng, Chin-Kai, Chen, Yeh-Long, Tzeng, Cherng-Chyi, Tseng, Chih-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278568/ https://www.ncbi.nlm.nih.gov/pubmed/30400244 http://dx.doi.org/10.3390/molecules23112863

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