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Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction

Skin cancer is currently diagnosed as one in every three cancers. Melanoma, the most aggressive form of skin cancer, is responsible for 79% of skin cancer deaths and the incidence is rising faster than in any other solid tumor type. Previously, we have demonstrated that dimethylacrylshikonin (DMAS),...

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Detalles Bibliográficos
Autores principales: Kretschmer, Nadine, Deutsch, Alexander, Durchschein, Christin, Rinner, Beate, Stallinger, Alexander, Higareda-Almaraz, Juan Carlos, Scheideler, Marcel, Lohberger, Birgit, Bauer, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278572/
https://www.ncbi.nlm.nih.gov/pubmed/30380804
http://dx.doi.org/10.3390/molecules23112823

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