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Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction
Skin cancer is currently diagnosed as one in every three cancers. Melanoma, the most aggressive form of skin cancer, is responsible for 79% of skin cancer deaths and the incidence is rising faster than in any other solid tumor type. Previously, we have demonstrated that dimethylacrylshikonin (DMAS),...
Autores principales: | Kretschmer, Nadine, Deutsch, Alexander, Durchschein, Christin, Rinner, Beate, Stallinger, Alexander, Higareda-Almaraz, Juan Carlos, Scheideler, Marcel, Lohberger, Birgit, Bauer, Rudolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278572/ https://www.ncbi.nlm.nih.gov/pubmed/30380804 http://dx.doi.org/10.3390/molecules23112823 |
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