Analogues of Muraymycin Nucleoside Antibiotics with Epimeric Uridine-Derived Core Structures

Nucleoside analogues have found widespread application as antiviral and antitumor agents, but not yet as antibacterials. Naturally occurring uridine-derived ‘nucleoside antibiotics’ target the bacterial membrane protein MraY, an enzyme involved in peptidoglycan biosynthesis and a promising target fo...

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Detalles Bibliográficos
Autores principales: Spork, Anatol P., Koppermann, Stefan, Schier (née Wohnig), Stephanie, Linder, Ruth, Ducho, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278576/
https://www.ncbi.nlm.nih.gov/pubmed/30400295
http://dx.doi.org/10.3390/molecules23112868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278576/
https://www.ncbi.nlm.nih.gov/pubmed/30400295
http://dx.doi.org/10.3390/molecules23112868

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