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PI3Kβ inhibitor AZD6482 exerts antiproliferative activity and induces apoptosis in human glioblastoma cells
Glioblastoma is the most common type of primary brain tumour in adults, and its pathogenesis is particularly complicated. Among the many possible mechanisms underlying its pathogenesis, hyperactivation of the PI3K/Akt pathway is essential to the occurrence and development of glioma through the loss...
Autores principales: | Xu, Peng-Fei, Yang, Ji-An, Liu, Jun-Hui, Yang, Xue, Liao, Jian-Ming, Yuan, Fan-En, Liu, Bao-Hui, Chen, Qian-Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278584/ https://www.ncbi.nlm.nih.gov/pubmed/30542720 http://dx.doi.org/10.3892/or.2018.6845 |
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