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The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)

BACKGROUND: The development and progression of hepatocellular carcinoma (HCC) are associated with obesity and hepatosteatosis. AMP-activated protein kinase (AMPK) regulates metabolic homeostasis. This study aimed to investigate the effects of treatment with the adenosine monophosphate (AMP) analog,...

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Detalles Bibliográficos
Autores principales:	Gao, Jianlong, Xiong, Rui, Xiong, Dan, Zhao, Wenxing, Zhang, Sheng, Yin, Tao, Zhang, Xinhua, Jiang, Guozhen, Yin, Zhenyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278641/ https://www.ncbi.nlm.nih.gov/pubmed/30474622 http://dx.doi.org/10.12659/MSM.910544

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