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Relationship between HIV integrase polymorphisms and integrase inhibitor susceptibility: An in silico analysis

Integrase (IN) plays an essential role in HIV-1 replication, by mediating integration of the viral genome into the host cell genome. IN is a potential target of antiretroviral (ARV) therapeutic drugs such as ALLINI, Raltegravir (RAL), and Elvitegravir (EVG). The effect of IN polymorphisms on its str...

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Detalles Bibliográficos
Autores principales:	Hutapea, Hotma Martogi Lorensi, Maladan, Yustinus, Widodo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278726/ https://www.ncbi.nlm.nih.gov/pubmed/30534615 http://dx.doi.org/10.1016/j.heliyon.2018.e00956

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