Inhibition of protein disulfide isomerase induces differentiation of acute myeloid leukemia cells

A cute myeloid leukemia is a malignant disease of immature myeloid cells. Despite significant therapeutic effects of differentiation-inducing agents in some acute myeloid leukemia subtypes, the disease remains incurable in a large fraction of patients. Here we show that SK053, a thioredoxin inhibito...

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Detalles Bibliográficos
Autores principales: Chlebowska-Tuz, Justyna, Sokolowska, Olga, Gaj, Pawel, Lazniewski, Michal, Firczuk, Malgorzata, Borowiec, Karolina, Sas-Nowosielska, Hanna, Bajor, Malgorzata, Malinowska, Agata, Muchowicz, Angelika, Ramji, Kavita, Stawinski, Piotr, Sobczak, Mateusz, Pilch, Zofia, Rodziewicz-Lurzynska, Anna, Zajac, Malgorzata, Giannopoulos, Krzysztof, Juszczynski, Przemyslaw, Basak, Grzegorz W., Plewczynski, Dariusz, Ploski, Rafal, Golab, Jakub, Nowis, Dominika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278960/
https://www.ncbi.nlm.nih.gov/pubmed/30002127
http://dx.doi.org/10.3324/haematol.2018.190231

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