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Preclinical human models and emerging therapeutics for advanced systemic mastocytosis

Mastocytosis is a term used to denote a group of rare diseases characterized by an abnormal accumulation of neoplastic mast cells in various tissues and organs. In most patients with systemic mastocytosis, the neoplastic cells carry activating mutations in KIT. Progress in mastocytosis research has...

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Detalles Bibliográficos
Autores principales: Arock, Michel, Wedeh, Ghaith, Hoermann, Gregor, Bibi, Siham, Akin, Cem, Peter, Barbara, Gleixner, Karoline V., Hartmann, Karin, Butterfield, Joseph H., Metcalfe, Dean D., Valent, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278969/
https://www.ncbi.nlm.nih.gov/pubmed/29976735
http://dx.doi.org/10.3324/haematol.2018.195867