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Three May Be Better Than Two: A Proposal for Metformin Addition to PI3K/Akt Inhibitor-antiandrogen Combination in Castration-resistant Prostate Cancer
Prostate cancer is a prevalent malignant disease. Castration-resistant prostate cancer (CRPC) is a poor prognosis form that develops upon resistance to first-line androgen deprivation therapy. Intensive research is ongoing to find efficient therapeutics for this refractory state. Actually, the combi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cureus
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278999/ https://www.ncbi.nlm.nih.gov/pubmed/30533337 http://dx.doi.org/10.7759/cureus.3403 |