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A Case of Sjögren's Syndrome Mimicking Inflammatory Myopathy

Sjögren's syndrome (SS) is a chronic autoimmune disorder, characterized by lymphocytic infiltration of exocrine glands and causing the decreased function of lacrimal and salivary glands. We describe a case of a 34-year-old male who presented with Sjögren's syndrome presenting as myopathy a...

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Autores principales: Khosa, Shaweta, Hovsepian, Dominic A, Khosa, Gurveer S, Catherine, Yim, Trikamji, Bhavesh, Mishra, Shri K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279011/
https://www.ncbi.nlm.nih.gov/pubmed/30533328
http://dx.doi.org/10.7759/cureus.3393
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author Khosa, Shaweta
Hovsepian, Dominic A
Khosa, Gurveer S
Catherine, Yim
Trikamji, Bhavesh
Mishra, Shri K
author_facet Khosa, Shaweta
Hovsepian, Dominic A
Khosa, Gurveer S
Catherine, Yim
Trikamji, Bhavesh
Mishra, Shri K
author_sort Khosa, Shaweta
collection PubMed
description Sjögren's syndrome (SS) is a chronic autoimmune disorder, characterized by lymphocytic infiltration of exocrine glands and causing the decreased function of lacrimal and salivary glands. We describe a case of a 34-year-old male who presented with Sjögren's syndrome presenting as myopathy and sensorimotor neuropathy. His creatinine kinase levels were elevated with positive anti-Sjögren's syndrome-related antigen A autoantibodies and anti-Sjögren's syndrome Type B autoantibodies. Electromyography showed evidence of irritable myopathy. Parotid gland biopsy demonstrated focal lymphocytic sialadenitis. The patient favorably responded to high-dose steroids. Thus, although rare, inflammatory myopathy must be considered part of the initial presentation of Sjögren's syndrome.
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spelling pubmed-62790112018-12-07 A Case of Sjögren's Syndrome Mimicking Inflammatory Myopathy Khosa, Shaweta Hovsepian, Dominic A Khosa, Gurveer S Catherine, Yim Trikamji, Bhavesh Mishra, Shri K Cureus Neurology Sjögren's syndrome (SS) is a chronic autoimmune disorder, characterized by lymphocytic infiltration of exocrine glands and causing the decreased function of lacrimal and salivary glands. We describe a case of a 34-year-old male who presented with Sjögren's syndrome presenting as myopathy and sensorimotor neuropathy. His creatinine kinase levels were elevated with positive anti-Sjögren's syndrome-related antigen A autoantibodies and anti-Sjögren's syndrome Type B autoantibodies. Electromyography showed evidence of irritable myopathy. Parotid gland biopsy demonstrated focal lymphocytic sialadenitis. The patient favorably responded to high-dose steroids. Thus, although rare, inflammatory myopathy must be considered part of the initial presentation of Sjögren's syndrome. Cureus 2018-10-01 /pmc/articles/PMC6279011/ /pubmed/30533328 http://dx.doi.org/10.7759/cureus.3393 Text en Copyright © 2018, Khosa et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Khosa, Shaweta
Hovsepian, Dominic A
Khosa, Gurveer S
Catherine, Yim
Trikamji, Bhavesh
Mishra, Shri K
A Case of Sjögren's Syndrome Mimicking Inflammatory Myopathy
title A Case of Sjögren's Syndrome Mimicking Inflammatory Myopathy
title_full A Case of Sjögren's Syndrome Mimicking Inflammatory Myopathy
title_fullStr A Case of Sjögren's Syndrome Mimicking Inflammatory Myopathy
title_full_unstemmed A Case of Sjögren's Syndrome Mimicking Inflammatory Myopathy
title_short A Case of Sjögren's Syndrome Mimicking Inflammatory Myopathy
title_sort case of sjögren's syndrome mimicking inflammatory myopathy
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279011/
https://www.ncbi.nlm.nih.gov/pubmed/30533328
http://dx.doi.org/10.7759/cureus.3393
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