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Current and future goals are represented in opposite patterns in object-selective cortex

Adaptive behavior requires the separation of current from future goals in working memory. We used fMRI of object-selective cortex to determine the representational (dis)similarities of memory representations serving current and prospective perceptual tasks. Participants remembered an object drawn fr...

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Autores principales: van Loon, Anouk Mariette, Olmos-Solis, Katya, Fahrenfort, Johannes Jacobus, Olivers, Christian NL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279347/
https://www.ncbi.nlm.nih.gov/pubmed/30394873
http://dx.doi.org/10.7554/eLife.38677
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author van Loon, Anouk Mariette
Olmos-Solis, Katya
Fahrenfort, Johannes Jacobus
Olivers, Christian NL
author_facet van Loon, Anouk Mariette
Olmos-Solis, Katya
Fahrenfort, Johannes Jacobus
Olivers, Christian NL
author_sort van Loon, Anouk Mariette
collection PubMed
description Adaptive behavior requires the separation of current from future goals in working memory. We used fMRI of object-selective cortex to determine the representational (dis)similarities of memory representations serving current and prospective perceptual tasks. Participants remembered an object drawn from three possible categories as the target for one of two consecutive visual search tasks. A cue indicated whether the target object should be looked for first (currently relevant), second (prospectively relevant), or if it could be forgotten (irrelevant). Prior to the first search, representations of current, prospective and irrelevant objects were similar, with strongest decoding for current representations compared to prospective (Experiment 1) and irrelevant (Experiment 2). Remarkably, during the first search, prospective representations could also be decoded, but revealed anti-correlated voxel patterns compared to currently relevant representations of the same category. We propose that the brain separates current from prospective memories within the same neuronal ensembles through opposite representational patterns.
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spelling pubmed-62793472018-12-05 Current and future goals are represented in opposite patterns in object-selective cortex van Loon, Anouk Mariette Olmos-Solis, Katya Fahrenfort, Johannes Jacobus Olivers, Christian NL eLife Neuroscience Adaptive behavior requires the separation of current from future goals in working memory. We used fMRI of object-selective cortex to determine the representational (dis)similarities of memory representations serving current and prospective perceptual tasks. Participants remembered an object drawn from three possible categories as the target for one of two consecutive visual search tasks. A cue indicated whether the target object should be looked for first (currently relevant), second (prospectively relevant), or if it could be forgotten (irrelevant). Prior to the first search, representations of current, prospective and irrelevant objects were similar, with strongest decoding for current representations compared to prospective (Experiment 1) and irrelevant (Experiment 2). Remarkably, during the first search, prospective representations could also be decoded, but revealed anti-correlated voxel patterns compared to currently relevant representations of the same category. We propose that the brain separates current from prospective memories within the same neuronal ensembles through opposite representational patterns. eLife Sciences Publications, Ltd 2018-11-06 /pmc/articles/PMC6279347/ /pubmed/30394873 http://dx.doi.org/10.7554/eLife.38677 Text en © 2018, van Loon et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
van Loon, Anouk Mariette
Olmos-Solis, Katya
Fahrenfort, Johannes Jacobus
Olivers, Christian NL
Current and future goals are represented in opposite patterns in object-selective cortex
title Current and future goals are represented in opposite patterns in object-selective cortex
title_full Current and future goals are represented in opposite patterns in object-selective cortex
title_fullStr Current and future goals are represented in opposite patterns in object-selective cortex
title_full_unstemmed Current and future goals are represented in opposite patterns in object-selective cortex
title_short Current and future goals are represented in opposite patterns in object-selective cortex
title_sort current and future goals are represented in opposite patterns in object-selective cortex
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279347/
https://www.ncbi.nlm.nih.gov/pubmed/30394873
http://dx.doi.org/10.7554/eLife.38677
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