Endothelial-specific FoxO1 depletion prevents obesity-related disorders by increasing vascular metabolism and growth

Impaired angiogenesis is a hallmark of metabolically dysfunctional adipose tissue in obesity. However, the underlying mechanisms restricting angiogenesis within this context remain ill-defined. Here, we demonstrate that induced endothelial-specific depletion of the transcription factor Forkhead Box...

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Detalles Bibliográficos
Autores principales: Rudnicki, Martina, Abdifarkosh, Ghoncheh, Nwadozi, Emmanuel, Ramos, Sofhia V, Makki, Armin, Sepa-Kishi, Diane M, Ceddia, Rolando B, Perry, Christopher GR, Roudier, Emilie, Haas, Tara L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279348/
https://www.ncbi.nlm.nih.gov/pubmed/30511639
http://dx.doi.org/10.7554/eLife.39780

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