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Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein

The ubiquitin-like protein Atg8, in its lipidated form, plays central roles in autophagy. Yet, remarkably, Atg8 also carries out lipidation-independent functions in non-autophagic processes. How Atg8 performs its moonlighting roles is unclear. Here we report that in the fission yeast Schizosaccharom...

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Detalles Bibliográficos
Autores principales:	Liu, Xiao-Man, Yamasaki, Akinori, Du, Xiao-Min, Coffman, Valerie C, Ohsumi, Yoshinori, Nakatogawa, Hitoshi, Wu, Jian-Qiu, Noda, Nobuo N, Du, Li-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279349/ https://www.ncbi.nlm.nih.gov/pubmed/30451685 http://dx.doi.org/10.7554/eLife.41237

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