Cargando…
Membrane fluidity is regulated by the C. elegans transmembrane protein FLD-1 and its human homologs TLCD1/2
Dietary fatty acids are the main building blocks for cell membranes in animals, and mechanisms must therefore exist that compensate for dietary variations. We isolated C. elegans mutants that improved tolerance to dietary saturated fat in a sensitized genetic background, including eight alleles of t...
Autores principales: | Ruiz, Mario, Bodhicharla, Rakesh, Svensk, Emma, Devkota, Ranjan, Busayavalasa, Kiran, Palmgren, Henrik, Ståhlman, Marcus, Boren, Jan, Pilon, Marc |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279351/ https://www.ncbi.nlm.nih.gov/pubmed/30509349 http://dx.doi.org/10.7554/eLife.40686 |
Ejemplares similares
-
Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity
por: Ruiz, Mario, et al.
Publicado: (2019) -
Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins
por: Busayavalasa, Kiran, et al.
Publicado: (2020) -
Membrane Fluidity Is Regulated Cell Nonautonomously by Caenorhabditis elegans PAQR-2 and Its Mammalian Homolog AdipoR2
por: Bodhicharla, Rakesh, et al.
Publicado: (2018) -
The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids
por: Devkota, Ranjan, et al.
Publicado: (2017) -
AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity
por: Ruiz, Mario, et al.
Publicado: (2023)