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Pore- and voltage sensor–targeted KCNQ openers have distinct state-dependent actions
Ion channels encoded by KCNQ2-5 generate a prominent K(+) conductance in the central nervous system, referred to as the M current, which is controlled by membrane voltage and PIP2. The KCNQ2-5 voltage-gated potassium channels are targeted by a variety of activating compounds that cause negative shif...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279353/ https://www.ncbi.nlm.nih.gov/pubmed/30373787 http://dx.doi.org/10.1085/jgp.201812070 |